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Effects of folic acid supplementation in pregnant mice on glucose metabolism disorders in male offspring induced by lipopolysaccharide exposure during pregnancy

The DOHaD theory suggests that adverse environmental factors in early life may lead to the development of metabolic diseases including diabetes and hypertension in adult offspring through epigenetic mechanisms such as DNA methylation. Folic acid (FA) is an important methyl donor in vivo and particip...

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Detalles Bibliográficos
Autores principales: Sun, Wan-Xiao, Shu, Yi-Ping, Yang, Xin-Yu, Huang, Wei, Chen, Jing, Yu, Ning-Ning, Zhao, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192134/
https://www.ncbi.nlm.nih.gov/pubmed/37198280
http://dx.doi.org/10.1038/s41598-023-31690-w