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Integrative Mendelian randomization reveals the soluble receptor for advanced glycation end products as protective in relation to rheumatoid arthritis

Rheumatoid arthritis (RA) is a risk factor for atherosclerotic cardiovascular diseases (CVD). Given the critical roles of the immune system and inflammatory signals in the pathogenesis of CVD, we hypothesized that interrogation of CVD-related proteins using integrative genomics might provide new ins...

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Detalles Bibliográficos
Autores principales: Lee, Gha Young, Yao, Chen, Hwang, Shih-Jen, Ma, Jiantao, Joehanes, Roby, Lee, Dong Heon, Ellison, R. Curtis, Moore, Lynn L., Liu, Chunyu, Levy, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192300/
https://www.ncbi.nlm.nih.gov/pubmed/37198231
http://dx.doi.org/10.1038/s41598-023-35098-4