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Strategies for precise gene edits in mammalian cells

CRISPR-Cas technologies have the potential to revolutionize genetic medicine. However, work is still needed to make this technology clinically efficient for gene correction. A barrier to making precise genetic edits in the human genome is controlling how CRISPR-Cas-induced DNA breaks are repaired by...

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Detalles Bibliográficos
Autores principales: Fichter, Katye M., Setayesh, Tahereh, Malik, Punam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192336/
https://www.ncbi.nlm.nih.gov/pubmed/37215153
http://dx.doi.org/10.1016/j.omtn.2023.04.012