Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9

A primary objective in malaria vaccine design is the generation of high-quality antibody responses against the circumsporozoite protein of the malaria parasite, Plasmodium falciparum (PfCSP). To enable rational antigen design, we solved a cryo-EM structure of the highly potent anti-PfCSP antibody L9...

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Detalles Bibliográficos
Autores principales: Martin, Gregory M., Fernández-Quintero, Monica L., Lee, Wen-Hsin, Pholcharee, Tossapol, Eshun-Wilson, Lisa, Liedl, Klaus R., Pancera, Marie, Seder, Robert A., Wilson, Ian A., Ward, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192352/
https://www.ncbi.nlm.nih.gov/pubmed/37198165
http://dx.doi.org/10.1038/s41467-023-38509-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192352/
https://www.ncbi.nlm.nih.gov/pubmed/37198165
http://dx.doi.org/10.1038/s41467-023-38509-2

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