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Biophysical characterization of adeno-associated virus capsid through the viral transduction life cycle

Adeno-associated virus (AAV) vectors have emerged as the leading delivery platforms for gene therapy. Throughout the life cycle of the virions, the capsid vector carries out diverse functions, ranging from cell surface receptor engagement, cellular entry, endosomal escape, nuclear import to new part...

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Detalles Bibliográficos
Autores principales: Xiang, Yanqiao Shawn, Hao, Gang Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192463/
https://www.ncbi.nlm.nih.gov/pubmed/37195476
http://dx.doi.org/10.1186/s43141-023-00518-5