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Biophysical characterization of adeno-associated virus capsid through the viral transduction life cycle
Adeno-associated virus (AAV) vectors have emerged as the leading delivery platforms for gene therapy. Throughout the life cycle of the virions, the capsid vector carries out diverse functions, ranging from cell surface receptor engagement, cellular entry, endosomal escape, nuclear import to new part...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192463/ https://www.ncbi.nlm.nih.gov/pubmed/37195476 http://dx.doi.org/10.1186/s43141-023-00518-5 |