Remodeled connexin 43 hemichannels alter cardiac excitability and promote arrhythmias

Connexin-43 (Cx43) is the most abundant protein forming gap junction channels (GJCs) in cardiac ventricles. In multiple cardiac pathologies, including hypertrophy and heart failure, Cx43 is found remodeled at the lateral side of the intercalated discs of ventricular cardiomyocytes. Remodeling of Cx4...

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Detalles Bibliográficos
Autores principales: Lillo, Mauricio A., Muñoz, Manuel, Rhana, Paula, Gaul-Muller, Kelli, Quan, Jonathan, Shirokova, Natalia, Xie, Lai-Hua, Santana, Luis Fernando, Fraidenraich, Diego, Contreras, Jorge E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192603/
https://www.ncbi.nlm.nih.gov/pubmed/37191672
http://dx.doi.org/10.1085/jgp.202213150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192603/
https://www.ncbi.nlm.nih.gov/pubmed/37191672
http://dx.doi.org/10.1085/jgp.202213150

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