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Network pharmacology reveals that Berberine may function against Alzheimer’s disease via the AKT signaling pathway

OBJECTIVE: To investigate the mechanism underlying the effects of berberine (BBR) in the treatment of Alzheimer’s disease (AD). METHODS: 3 × Tg AD mice were treated with BBR for 3 months, then the open field test (OFT), the novel object recognition test (NOR) and the Morris water maze (MWM) test wer...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Yao, Jiu-xiu, Zhang, Ting-ting, Wen, Jia-yu, Zhang, Zhen, Luo, Yi-miao, Cao, Yu, Li, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192713/
https://www.ncbi.nlm.nih.gov/pubmed/37214397
http://dx.doi.org/10.3389/fnins.2023.1059496