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Biocompatibility of the oxygen carrier polymerized human hemoglobin towards HepG2/C3A cells

Hemoglobin (Hb) based oxygen carriers (HBOCs) are designed to minimize the toxicity of extracellular Hb, while preserving its high oxygen-carrying capacity for oxygen delivery to cells. Polymerized human Hb (PolyHb) is a novel type of nanosized HBOC synthesized via glutaraldehyde-mediated crosslinki...

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Detalles Bibliográficos
Autores principales: Chen, Nuozhou, Belcher, Donald A., Savla, Chintan, Palmer, Andre F., Berthiaume, Francois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192743/
https://www.ncbi.nlm.nih.gov/pubmed/37215914
http://dx.doi.org/10.1016/j.heliyon.2023.e15878