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Remission of social behavior impairment by oral administration of a precursor of NAD in CD157, but not in CD38, knockout mice
Nicotinamide adenine dinucleotide (NAD) is a substrate of adenosine diphosphate (ADP)-ribosyl cyclase and is catalyzed to cyclic ADP-ribose (cADPR) by CD38 and/or CD157. cADPR, a Ca(2+) mobilizing second messenger, is critical in releasing oxytocin from the hypothalamus into the brain. Although NAD...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192747/ https://www.ncbi.nlm.nih.gov/pubmed/37215105 http://dx.doi.org/10.3389/fimmu.2023.1166609 |