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Benzo[a]pyrene induces NLRP1 expression and promotes prolonged inflammasome signaling

Benzo[a]pyrene (BaP), a polycyclic aromatic hydrocarbon in the air, triggers pulmonary inflammation. This study focused on BaP-induced inflammation in the alveolar epithelium. A549 cells were stimulated with BaP for four days. BaP treatment markedly increased NLRP1 expression but slightly decreased...

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Detalles Bibliográficos
Autores principales: Kohno, Risa, Nagata, Yuka, Ishihara, Tomohiro, Amma, Chisato, Inomata, Yayoi, Seto, Takafumi, Suzuki, Ryo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192748/
https://www.ncbi.nlm.nih.gov/pubmed/37215119
http://dx.doi.org/10.3389/fimmu.2023.1154857