Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrest

Connexin37-mediated regulation of cell cycle modulators and, consequently, growth arrest lack mechanistic understanding. We previously showed that arterial shear stress up-regulates Cx37 in endothelial cells and activates a Notch/Cx37/p27 signaling axis to promote G1 cell cycle arrest, and this is r...

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Detalles Bibliográficos
Autores principales: Acharya, Bipul R, Fang, Jennifer S, Jeffery, Erin D, Chavkin, Nicholas W, Genet, Gael, Vasavada, Hema, Nelson, Elizabeth A, Sheynkman, Gloria M, Humphries, Martin J, Hirschi, Karen K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192821/
https://www.ncbi.nlm.nih.gov/pubmed/37197981
http://dx.doi.org/10.26508/lsa.202201685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192821/
https://www.ncbi.nlm.nih.gov/pubmed/37197981
http://dx.doi.org/10.26508/lsa.202201685

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