Rapid, scalable assay of amylin-β amyloid co-aggregation in brain tissue and blood

Islet amyloid polypeptide (amylin) secreted from the pancreas crosses from the blood to the brain parenchyma and forms cerebral mixed amylin-β amyloid (Aβ) plaques in persons with Alzheimer’s disease (AD). Cerebral amylin-Aβ plaques are found in both sporadic and early-onset familial AD; however, th...

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Detalles Bibliográficos
Autores principales: Kotiya, Deepak, Leibold, Noah, Verma, Nirmal, Jicha, Gregory A., Goldstein, Larry B., Despa, Florin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article Collection: Neurobiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192925/
https://www.ncbi.nlm.nih.gov/pubmed/37030503
http://dx.doi.org/10.1016/j.jbc.2023.104682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192925/
https://www.ncbi.nlm.nih.gov/pubmed/37030503
http://dx.doi.org/10.1016/j.jbc.2023.104682

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