Targeting MYC in combination with epigenetic regulators induces synergistic anti-leukemic effects in MLLr leukemia and simultaneously improves immunity

MLL rearranged (MLLr) leukemias are associated with a poor prognosis and a limited response to conventional therapies. Moreover, chemotherapies result in severe side effects with significant impairment of the immune system. Therefore, the identification of novel treatment strategies is mandatory. Re...

Descripción completa

Detalles Bibliográficos
Autores principales: Fitzel, Rahel, Secker-Grob, Kathy-Ann, Keppeler, Hildegard, Korkmaz, Fulya, Schairer, Rebekka, Erkner, Estelle, Schneidawind, Dominik, Lengerke, Claudia, Hentrich, Thomas, Schulze-Hentrich, Julia M., Schneidawind, Corina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192941/
https://www.ncbi.nlm.nih.gov/pubmed/37148657
http://dx.doi.org/10.1016/j.neo.2023.100902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192941/
https://www.ncbi.nlm.nih.gov/pubmed/37148657
http://dx.doi.org/10.1016/j.neo.2023.100902

Ejemplares similares