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Teaching an old dog new tricks: A new tool for protein tyrosine phosphatase substrate discovery
The identification of substrates for protein tyrosine phosphatases (PTPs) is critical for a complete understanding of how these enzymes function. In a recent study in the JBC, Bonham et al. developed a modified method combining substrate-trapping mutations with proximity-labeling MS to identify the...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Society for Biochemistry and Molecular Biology
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193000/ https://www.ncbi.nlm.nih.gov/pubmed/37080392 http://dx.doi.org/10.1016/j.jbc.2023.104731 |