Brain insulin signaling suppresses lipolysis in the absence of peripheral insulin receptors and requires the MAPK pathway

OBJECTIVES: Insulin's ability to counterbalance catecholamine-induced lipolysis defines insulin action in adipose tissue. Insulin suppresses lipolysis directly at the level of the adipocyte and indirectly through signaling in the brain. Here, we further characterized the role of brain insulin s...

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Detalles Bibliográficos
Autores principales: Metz, Matthäus, O'Hare, James, Cheng, Bob, Puchowicz, Michelle, Buettner, Christoph, Scherer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193009/
https://www.ncbi.nlm.nih.gov/pubmed/37100238
http://dx.doi.org/10.1016/j.molmet.2023.101723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193009/
https://www.ncbi.nlm.nih.gov/pubmed/37100238
http://dx.doi.org/10.1016/j.molmet.2023.101723

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