TP53BP1, a dual-coding gene, uses promoter switching and translational reinitiation to express a smORF protein

The complexity of the metazoan proteome is significantly increased by the expression of small proteins (<100 aa) derived from smORFs within lncRNAs, uORFs, 3′ UTRs and, reading frames overlapping the CDS. These smORF encoded proteins (SEPs) have diverse roles, ranging from the regulation of cellu...

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Detalles Bibliográficos
Autores principales: Inchingolo, Marta A., Diman, Aurélie, Adamczewski, Maxime, Humphreys, Tom, Jaquier-Gubler, Pascale, Curran, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193022/
https://www.ncbi.nlm.nih.gov/pubmed/37216125
http://dx.doi.org/10.1016/j.isci.2023.106757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193022/
https://www.ncbi.nlm.nih.gov/pubmed/37216125
http://dx.doi.org/10.1016/j.isci.2023.106757

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