Genome-wide mRNA profiling in urinary extracellular vesicles reveals stress gene signature for diabetic kidney disease

Urinary extracellular vesicles (uEV) are a largely unexplored source of kidney-derived mRNAs with potential to serve as a liquid kidney biopsy. We assessed ∼200 uEV mRNA samples from clinical studies by genome-wide sequencing to discover mechanisms and candidate biomarkers of diabetic kidney disease...

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Detalles Bibliográficos
Autores principales: Dwivedi, Om Prakash, Barreiro, Karina, Käräjämäki, Annemari, Valo, Erkka, Giri, Anil K., Prasad, Rashmi B., Roy, Rishi Das, Thorn, Lena M., Rannikko, Antti, Holthöfer, Harry, Gooding, Kim M., Sourbron, Steven, Delic, Denis, Gomez, Maria F., Groop, Per-Henrik, Tuomi, Tiinamaija, Forsblom, Carol, Groop, Leif, Puhka, Maija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193229/
https://www.ncbi.nlm.nih.gov/pubmed/37216114
http://dx.doi.org/10.1016/j.isci.2023.106686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193229/
https://www.ncbi.nlm.nih.gov/pubmed/37216114
http://dx.doi.org/10.1016/j.isci.2023.106686

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