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Mechanisms regulating the loss of Tregs in HUPO mice that develop spontaneous inflammatory arthritis

T regulatory cells (Tregs) are a potential therapeutic target in many autoimmune diseases including rheumatoid arthritis (RA). The mechanisms responsible for the maintenance of Tregs in chronic inflammatory conditions such as RA are poorly understood. We employed our mouse model of RA in which, the...

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Detalles Bibliográficos
Autores principales: Huang, Qi-Quan, Hang, Yiwei, Doyle, Renee, Mao, Qinwen, Fang, Deyu, Pope, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193230/
https://www.ncbi.nlm.nih.gov/pubmed/37216119
http://dx.doi.org/10.1016/j.isci.2023.106734