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Stress granules affect the sensitivity of renal cancer cells to sorafenib by sequestering and stabilizing COX‑2 mRNA

Most patients with renal cancer will develop resistance to sorafenib therapy and will therefore exhibit disease progression. Effective therapies for these patients are extremely limited. Cyclooxygenase-2 (COX-2) promotes the malignant transformation of cancer cells and drug resistance. The potential...

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Detalles Bibliográficos
Autores principales: Dai, Huiqi, Wang, Guoli, Cao, Wenmin, Qi, Wei, Chen, Wei, Guo, Hongqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193378/
https://www.ncbi.nlm.nih.gov/pubmed/37216166
http://dx.doi.org/10.3892/ol.2023.13860