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Evaluation of (89)Zr-Labeled Anti-PD-L1 Monoclonal Antibodies Using DFO and Novel HOPO Analogues as Chelating Agents for Immuno-PET

[Image: see text] Programmed death ligand 1 (PD-L1) is a type 1 transmembrane immunosuppressive protein that is expressed on a wide range of cell types, including cancer cells. Anti-PD-L1 antibodies have revolutionized cancer therapy and have led to improved outcomes for subsets of cancer patients,...

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Detalles Bibliográficos
Autores principales: Radaram, Bhasker, Glazer, Sarah E., Yang, Ping, Li, Chia-Wei, Hung, Mien-Chie, Gammon, Seth T., Alauddin, Mian, Piwnica-Worms, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193402/
https://www.ncbi.nlm.nih.gov/pubmed/37214681
http://dx.doi.org/10.1021/acsomega.3c01547