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Evaluation of (89)Zr-Labeled Anti-PD-L1 Monoclonal Antibodies Using DFO and Novel HOPO Analogues as Chelating Agents for Immuno-PET
[Image: see text] Programmed death ligand 1 (PD-L1) is a type 1 transmembrane immunosuppressive protein that is expressed on a wide range of cell types, including cancer cells. Anti-PD-L1 antibodies have revolutionized cancer therapy and have led to improved outcomes for subsets of cancer patients,...
Autores principales: | Radaram, Bhasker, Glazer, Sarah E., Yang, Ping, Li, Chia-Wei, Hung, Mien-Chie, Gammon, Seth T., Alauddin, Mian, Piwnica-Worms, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193402/ https://www.ncbi.nlm.nih.gov/pubmed/37214681 http://dx.doi.org/10.1021/acsomega.3c01547 |
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