Discovery of Novel Tetrazoles Featuring a Pyrazole Moiety as Potent and Highly Selective Antifungal Agents

[Image: see text] In pursuit of developing novel azole antifungals with potent activity and high selectivity, a series of (2R,3S)-3-(substituted-1H-pyrazol-3-yl)-2-(2,4-difluorophenyl)-1-(1H-tetrazol-1-yl)butan-2-ol derivatives were designed and synthesized based on our previous work. All compounds...

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Detalles Bibliográficos
Autores principales: Chi, Xiaochen, Zhang, Haonan, Wu, Hao, Li, Xianru, Li, Liping, Jiang, Yuanying, Ni, Tingjunhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193422/
https://www.ncbi.nlm.nih.gov/pubmed/37214706
http://dx.doi.org/10.1021/acsomega.3c01421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193422/
https://www.ncbi.nlm.nih.gov/pubmed/37214706
http://dx.doi.org/10.1021/acsomega.3c01421

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