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Scalable culture techniques to generate large numbers of purified human Schwann cells for clinical trials in human spinal cord and peripheral nerve injuries

OBJECTIVE: Schwann cells (SCs) have been shown to play an essential role in axon regeneration in both peripheral nerve injuries (PNIs) and spinal cord injuries (SCIs). The transplantation of SCs as an adjunctive therapy is currently under investigation in human clinical trials due to their regenerat...

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Detalles Bibliográficos
Autores principales: Khan, Aisha, Diaz, Anthony, Brooks, Adriana E., Burks, S. Shelby, Athauda, Gagani, Wood, Patrick, Lee, Yee-Shuan, Silvera, Risset, Donaldson, Maxwell, Pressman, Yelena, Anderson, Kim D., Bunge, Mary Bartlett, Pearse, Damien D., Dietrich, W. Dalton, Guest, James D., Levi, Allan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neurological Surgeons 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193489/
https://www.ncbi.nlm.nih.gov/pubmed/34479193
http://dx.doi.org/10.3171/2020.11.SPINE201433