Cargando…

Chemical Activation and Mechanical Sensitization of Piezo1 Enhance TRAIL-Mediated Apoptosis in Glioblastoma Cells

[Image: see text] Glioblastoma multiforme (GBM), the most common and aggressive type of primary brain tumor, has a mean survival of less than 15 months after standard treatment. Treatment with the current standard of care, temozolomide (TMZ), may be ineffective if damaged tumor cells undergo DNA rep...

Descripción completa

Detalles Bibliográficos
Autores principales: Knoblauch, Samantha V., Desai, Shanay H., Dombroski, Jenna A., Sarna, Nicole S., Hope, Jacob M., King, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193566/
https://www.ncbi.nlm.nih.gov/pubmed/37214705
http://dx.doi.org/10.1021/acsomega.3c00705