Chemical Activation and Mechanical Sensitization of Piezo1 Enhance TRAIL-Mediated Apoptosis in Glioblastoma Cells

[Image: see text] Glioblastoma multiforme (GBM), the most common and aggressive type of primary brain tumor, has a mean survival of less than 15 months after standard treatment. Treatment with the current standard of care, temozolomide (TMZ), may be ineffective if damaged tumor cells undergo DNA rep...

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Detalles Bibliográficos
Autores principales: Knoblauch, Samantha V., Desai, Shanay H., Dombroski, Jenna A., Sarna, Nicole S., Hope, Jacob M., King, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193566/
https://www.ncbi.nlm.nih.gov/pubmed/37214705
http://dx.doi.org/10.1021/acsomega.3c00705

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