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Quinolone-3-amidoalkanol: A New Class of Potent and Broad-Spectrum Antimicrobial Agent

[Image: see text] Herein, we describe 39 novel quinolone compounds bearing a hydrophilic amine chain and varied substituted benzyloxy units. These compounds demonstrate broad-spectrum activities against acid-fast bacterium, Gram-positive and -negative bacteria, fungi, and leishmania parasite. Compou...

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Detalles Bibliográficos
Autores principales: Dube, Phelelisiwe S., Angula, Klaudia T., Legoabe, Lesetja J., Jordaan, Audrey, Boitz Zarella, Jan M., Warner, Digby F., Doggett, J. Stone, Beteck, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193574/
https://www.ncbi.nlm.nih.gov/pubmed/37214682
http://dx.doi.org/10.1021/acsomega.3c01406