PKD2/polycystin-2 inhibits LPS-induced acute lung injury in vitro and in vivo by activating autophagy

Polycystin-2 (PC2), which is a transmembrane protein encoded by the PKD2 gene, plays an important role in kidney disease, but its role in lipopolysaccharide (LPS)-induced acute lung injury (ALI) is unclear. We overexpressed PKD2 in lung epithelial cells in vitro and in vivo and examined the role of...

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Detalles Bibliográficos
Autores principales: Pan, Fan, Bu, Lina, Wu, Kaixuan, Wang, Aizhong, Xu, Xiaotao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193782/
https://www.ncbi.nlm.nih.gov/pubmed/37198573
http://dx.doi.org/10.1186/s12890-023-02449-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193782/
https://www.ncbi.nlm.nih.gov/pubmed/37198573
http://dx.doi.org/10.1186/s12890-023-02449-w

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