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PKD2/polycystin-2 inhibits LPS-induced acute lung injury in vitro and in vivo by activating autophagy
Polycystin-2 (PC2), which is a transmembrane protein encoded by the PKD2 gene, plays an important role in kidney disease, but its role in lipopolysaccharide (LPS)-induced acute lung injury (ALI) is unclear. We overexpressed PKD2 in lung epithelial cells in vitro and in vivo and examined the role of...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193782/ https://www.ncbi.nlm.nih.gov/pubmed/37198573 http://dx.doi.org/10.1186/s12890-023-02449-w |