Unwinding mechanism of SARS-CoV helicase (nsp13) in the presence of Ca(2+), elucidated by biochemical and single-molecular studies

The recent outbreak of COVID-19 has created a serious health crisis with fatFal infectious viral diseases, such as Severe Acute Respiratory Syndrome (SARS). The nsp13, a helicase of coronaviruses is an essential element for viral replication that unwinds secondary structures of DNA and RNA, and is t...

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Detalles Bibliográficos
Autores principales: Yu, Jeongmin, Im, Hyeryeon, Lee, Gwangrog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193821/
https://www.ncbi.nlm.nih.gov/pubmed/37235917
http://dx.doi.org/10.1016/j.bbrc.2023.05.062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193821/
https://www.ncbi.nlm.nih.gov/pubmed/37235917
http://dx.doi.org/10.1016/j.bbrc.2023.05.062

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