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Unwinding mechanism of SARS-CoV helicase (nsp13) in the presence of Ca(2+), elucidated by biochemical and single-molecular studies
The recent outbreak of COVID-19 has created a serious health crisis with fatFal infectious viral diseases, such as Severe Acute Respiratory Syndrome (SARS). The nsp13, a helicase of coronaviruses is an essential element for viral replication that unwinds secondary structures of DNA and RNA, and is t...
Autores principales: | Yu, Jeongmin, Im, Hyeryeon, Lee, Gwangrog |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193821/ https://www.ncbi.nlm.nih.gov/pubmed/37235917 http://dx.doi.org/10.1016/j.bbrc.2023.05.062 |
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