CDYL reinforces male gonadal sex determination through epigenetically repressing Wnt4 transcription in mice

In mammals, male and female gonads initially develop from bipotential progenitor cells, which can differentiate into either testicular or ovarian cells. The decision to adopt a testicular or ovarian fate relies on robust genetic forces, i.e., activation of the testis-determining gene Sry, as well as...

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Detalles Bibliográficos
Autores principales: Okashita, Naoki, Maeda, Ryo, Tachibana, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193937/
https://www.ncbi.nlm.nih.gov/pubmed/37155872
http://dx.doi.org/10.1073/pnas.2221499120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193937/
https://www.ncbi.nlm.nih.gov/pubmed/37155872
http://dx.doi.org/10.1073/pnas.2221499120

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