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CDYL reinforces male gonadal sex determination through epigenetically repressing Wnt4 transcription in mice
In mammals, male and female gonads initially develop from bipotential progenitor cells, which can differentiate into either testicular or ovarian cells. The decision to adopt a testicular or ovarian fate relies on robust genetic forces, i.e., activation of the testis-determining gene Sry, as well as...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193937/ https://www.ncbi.nlm.nih.gov/pubmed/37155872 http://dx.doi.org/10.1073/pnas.2221499120 |