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The RPA–RNF20–SNF2H cascade promotes proper chromosome segregation and homologous recombination repair

The human tumor suppressor Ring finger protein 20 (RNF20)-mediated histone H2B monoubiquitination (H2Bub) is essential for proper chromosome segregation and DNA repair. However, what is the precise function and mechanism of RNF20–H2Bub in chromosome segregation and how this pathway is activated to p...

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Detalles Bibliográficos
Autores principales: Li, Jimin, Zhao, Jingyu, Gan, Xiaoli, Wang, Yanyan, Jiang, Donghao, Chen, Liang, Wang, Fangwei, Xu, Jingyan, Pei, Huadong, Huang, Jun, Chen, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193940/
https://www.ncbi.nlm.nih.gov/pubmed/37155876
http://dx.doi.org/10.1073/pnas.2303479120