Cargando…

The RPA–RNF20–SNF2H cascade promotes proper chromosome segregation and homologous recombination repair

The human tumor suppressor Ring finger protein 20 (RNF20)-mediated histone H2B monoubiquitination (H2Bub) is essential for proper chromosome segregation and DNA repair. However, what is the precise function and mechanism of RNF20–H2Bub in chromosome segregation and how this pathway is activated to p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Jimin, Zhao, Jingyu, Gan, Xiaoli, Wang, Yanyan, Jiang, Donghao, Chen, Liang, Wang, Fangwei, Xu, Jingyan, Pei, Huadong, Huang, Jun, Chen, Xuefeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193940/ https://www.ncbi.nlm.nih.gov/pubmed/37155876 http://dx.doi.org/10.1073/pnas.2303479120

Ejemplares similares

Proper RPA acetylation promotes accurate DNA replication and repair
por: Gan, Xiaoli, et al.
Publicado: (2023)

Maintaining chromosome and genome stability by the RPA–RNF20–SNF2H cascade
por: Driscoll, Garrett, et al.
Publicado: (2023)

Bre1/RNF20 promotes Rad51-mediated strand exchange and antagonizes the Srs2/FBH1 helicases
por: Liu, Guangxue, et al.
Publicado: (2023)

An Aurora B-RPA signaling axis secures chromosome segregation fidelity
por: Roshan, Poonam, et al.
Publicado: (2023)

RPA homologs and ssDNA processing during meiotic recombination
por: Ribeiro, Jonathan, et al.
Publicado: (2015)

RNF20-SNF2H Pathway of Chromatin Relaxation in DNA Double-Strand Break Repair
por: Kato, Akihiro, et al.
Publicado: (2015)

CTCF is essential for proper mitotic spindle structure and anaphase segregation
por: Chiu, Katherine, et al.
Publicado: (2023)

The genomic stability regulator PTIP is required for proper chromosome segregation in mitosis
por: Zhang, Fengxia, et al.
Publicado: (2022)

Germline landscape of RPA1, RPA2 and RPA3 variants in pediatric malignancies: identification of RPA1 as a novel cancer predisposition candidate gene
por: Sharma, Richa, et al.
Publicado: (2023)

Protein kinases required for proper segregation of chromosomes during meiosis
por: Pozgajova, Miroslava, et al.
Publicado: (2013)

Divergent Roles of RPA Homologs of the Model Archaeon Halobacterium salinarum in Survival of DNA Damage
por: Evans, Jessica J., et al.
Publicado: (2018)

Yeast Bromodomain Factor 1 and Its Human Homolog TAF1 Play Conserved Roles in Promoting Homologous Recombination
por: Peng, Haoyang, et al.
Publicado: (2021)

rough deal: a gene required for proper mitotic segregation in Drosophila
Publicado: (1989)

Dissociation of membrane–chromatin contacts is required for proper chromosome segregation in mitosis
por: Champion, Lysie, et al.
Publicado: (2019)

Nuclear Isoforms of Neurofibromin Are Required for Proper Spindle Organization and Chromosome Segregation
por: Peta, Charoula, et al.
Publicado: (2020)

Remote Homology Detection Identifies a Eukaryotic RPA DBD-C-like DNA Binding Domain as a Conserved Feature of Archaeal Rpa1-Like Proteins
por: MacNeill, Stuart A.
Publicado: (2021)

Global crotonylome reveals CDYL-regulated RPA1 crotonylation in homologous recombination–mediated DNA repair
por: Yu, Huajing, et al.
Publicado: (2020)

CDK-mediated RNF4 phosphorylation regulates homologous recombination in S-phase
por: Luo, Kuntian, et al.
Publicado: (2015)

The RNF8 and RNF168 Ubiquitin Ligases Regulate Pro- and Anti-Resection Activities at Broken DNA Ends During Non-Homologous End Joining
por: Chen, Bo-Ruei, et al.
Publicado: (2021)

The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation
por: Kline, Susan L., et al.
Publicado: (2006)

PLP inhibits the activity of interphase centrosomes to ensure their proper segregation in stem cells
por: Lerit, Dorothy A., et al.
Publicado: (2013)

ETAA1 ensures proper chromosome segregation: A matter of S phase or mitosis?
por: González Besteiro, Marina Alejandra, et al.
Publicado: (2019)

ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase
por: Mayer, Faith V., et al.
Publicado: (2011)

The condensin complex is required for proper spindle assembly and chromosome segregation in Xenopus egg extracts
por: Wignall, Sarah M., et al.
Publicado: (2003)

Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation
por: Kuga, T, et al.
Publicado: (2014)

Nuclear envelope expansion is crucial for proper chromosomal segregation during a closed mitosis
por: Takemoto, Ai, et al.
Publicado: (2016)

The negatively charged carboxy-terminal tail of β-tubulin promotes proper chromosome segregation
por: Fees, Colby P., et al.
Publicado: (2016)

Bromodomain-containing subunits BRD1, BRD2, and BRD13 are required for proper functioning of SWI/SNF complexes in Arabidopsis
por: Jarończyk, Kamila, et al.
Publicado: (2021)

HARP preferentially co-purifies with RPA bound to DNA-PK and blocks RPA phosphorylation
por: Quan, Jinhua, et al.
Publicado: (2014)

A naturally occurring human RPA subunit homolog does not support DNA replication or cell-cycle progression
por: Haring, Stuart J., et al.
Publicado: (2010)

Renormalized RPA at finite temperature
por: Avdeenkov, A V, et al.
Publicado: (1995)

Aquarius is required for proper CtIP expression and homologous recombination repair
por: Sakasai, Ryo, et al.
Publicado: (2017)

Mechanochemical regulations of RPA's binding to ssDNA
por: Chen, Jin, et al.
Publicado: (2015)

Initial dose cascade of TTS fentanyl with proper adjuvant medications in cancer pain.
por: Baik, Seong Wan, et al.
Publicado: (2003)

A Key Tumor Suppressor Protein Ensures Proper Chromosome Segregation during Cell Division
por: Hoff, Mary
Publicado: (2006)

Complex polar machinery required for proper chromosome segregation in vegetative and sporulating cells of Bacillus subtilis
por: Kloosterman, Tomas G., et al.
Publicado: (2016)

CENP-V is required for proper chromosome segregation through interaction with spindle microtubules in mouse oocytes
por: Nabi, Dalileh, et al.
Publicado: (2021)

Plk1 is essential for proper chromosome segregation during meiosis I/meiosis II transition in pig oocytes
por: Zhang, Zixiao, et al.
Publicado: (2017)

The Role of Tissue-Specific Ubiquitin Ligases, RNF183, RNF186, RNF182 and RNF152, in Disease and Biological Function
por: Okamoto, Takumi, et al.
Publicado: (2020)

The Genomic Landscape of the Fungus-Specific SWI/SNF Complex Subunit, Snf6, in Candida albicans
por: Tebbji, Faiza, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_c4692ksgu8spqjbhmbtf1ci2as