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Digital microfluidics-based digital counting of single-cell copy number variation (dd-scCNV Seq)
Single-cell copy number variations (CNVs), major dynamic changes in humans, result in differential levels of gene expression and account for adaptive traits or underlying disease. Single-cell sequencing is needed to reveal these CNVs but has been hindered by single-cell whole-genome amplification (s...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193948/ https://www.ncbi.nlm.nih.gov/pubmed/37155890 http://dx.doi.org/10.1073/pnas.2221934120 |