TRAF4-mediated nonproteolytic ubiquitination of androgen receptor promotes castration-resistant prostate cancer

Castration-resistant prostate cancer (CRPC) poses a major clinical challenge with the androgen receptor (AR) remaining to be a critical oncogenic player. Several lines of evidence indicate that AR induces a distinct transcriptional program after androgen deprivation in CRPCs. However, the mechanism...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Ramesh, Meng, Huan, Shen, Tao, Lumahan, Lance Edward V., Nguyen, Steven, Shen, Hong, Dasgupta, Subhamoy, Qin, Li, Karri, Dileep, Zhu, Bokai, Yang, Feng, Coarfa, Cristian, O’Malley, Bert W., Yi, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193960/
https://www.ncbi.nlm.nih.gov/pubmed/37155905
http://dx.doi.org/10.1073/pnas.2218229120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193960/
https://www.ncbi.nlm.nih.gov/pubmed/37155905
http://dx.doi.org/10.1073/pnas.2218229120

Ejemplares similares