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TRAF4-mediated nonproteolytic ubiquitination of androgen receptor promotes castration-resistant prostate cancer

Castration-resistant prostate cancer (CRPC) poses a major clinical challenge with the androgen receptor (AR) remaining to be a critical oncogenic player. Several lines of evidence indicate that AR induces a distinct transcriptional program after androgen deprivation in CRPCs. However, the mechanism...

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Detalles Bibliográficos
Autores principales:	Singh, Ramesh, Meng, Huan, Shen, Tao, Lumahan, Lance Edward V., Nguyen, Steven, Shen, Hong, Dasgupta, Subhamoy, Qin, Li, Karri, Dileep, Zhu, Bokai, Yang, Feng, Coarfa, Cristian, O’Malley, Bert W., Yi, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193960/ https://www.ncbi.nlm.nih.gov/pubmed/37155905 http://dx.doi.org/10.1073/pnas.2218229120

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