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Circular RNA vaccine induces potent T cell responses

Circular RNAs (circRNAs) are a class of RNAs commonly found across eukaryotes and viruses, characterized by their resistance to exonuclease-mediated degradation. Their superior stability compared to linear RNAs, combined with previous work showing that engineered circRNAs serve as efficient protein...

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Detalles Bibliográficos
Autores principales: Amaya, Laura, Grigoryan, Lilit, Li, Zhijian, Lee, Audrey, Wender, Paul A., Pulendran, Bali, Chang, Howard Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193964/
https://www.ncbi.nlm.nih.gov/pubmed/37155869
http://dx.doi.org/10.1073/pnas.2302191120