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Structure of WNT inhibitor adenomatosis polyposis coli down-regulated 1 (APCDD1), a cell-surface lipid-binding protein

Diverse extracellular proteins negatively regulate WNT signaling. One such regulator is adenomatosis polyposis coli down-regulated 1 (APCDD1), a conserved single-span transmembrane protein. In response to WNT signaling in a variety of tissues, APCDD1 transcripts are highly up-regulated. We have dete...

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Detalles Bibliográficos
Autores principales: Hsieh, Fu-Lien, Chang, Tao-Hsin, Gabelli, Sandra B., Nathans, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193966/
https://www.ncbi.nlm.nih.gov/pubmed/37155902
http://dx.doi.org/10.1073/pnas.2217096120