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Structure of WNT inhibitor adenomatosis polyposis coli down-regulated 1 (APCDD1), a cell-surface lipid-binding protein
Diverse extracellular proteins negatively regulate WNT signaling. One such regulator is adenomatosis polyposis coli down-regulated 1 (APCDD1), a conserved single-span transmembrane protein. In response to WNT signaling in a variety of tissues, APCDD1 transcripts are highly up-regulated. We have dete...
Autores principales: | Hsieh, Fu-Lien, Chang, Tao-Hsin, Gabelli, Sandra B., Nathans, Jeremy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193966/ https://www.ncbi.nlm.nih.gov/pubmed/37155902 http://dx.doi.org/10.1073/pnas.2217096120 |
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