Cargando…

A single-cell multiomic analysis of kidney organoid differentiation

Kidney organoids differentiated from pluripotent stem cells are powerful models of kidney development and disease but are characterized by cell immaturity and off-target cell fates. Comparing the cell-specific gene regulatory landscape during organoid differentiation with human adult kidney can serv...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoshimura, Yasuhiro, Muto, Yoshiharu, Ledru, Nicolas, Wu, Haojia, Omachi, Kohei, Miner, Jeffrey H., Humphreys, Benjamin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193973/
https://www.ncbi.nlm.nih.gov/pubmed/37155865
http://dx.doi.org/10.1073/pnas.2219699120