Cargando…
A single-cell multiomic analysis of kidney organoid differentiation
Kidney organoids differentiated from pluripotent stem cells are powerful models of kidney development and disease but are characterized by cell immaturity and off-target cell fates. Comparing the cell-specific gene regulatory landscape during organoid differentiation with human adult kidney can serv...
Autores principales: | Yoshimura, Yasuhiro, Muto, Yoshiharu, Ledru, Nicolas, Wu, Haojia, Omachi, Kohei, Miner, Jeffrey H., Humphreys, Benjamin D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193973/ https://www.ncbi.nlm.nih.gov/pubmed/37155865 http://dx.doi.org/10.1073/pnas.2219699120 |
Ejemplares similares
-
Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney
por: Muto, Yoshiharu, et al.
Publicado: (2021) -
Human Pluripotent Stem Cell-Derived Kidney Organoids with Improved Collecting Duct Maturation and Injury Modeling
por: Uchimura, Kohei, et al.
Publicado: (2020) -
The single-cell transcriptomic landscape of early human diabetic nephropathy
por: Wilson, Parker C., et al.
Publicado: (2019) -
Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis
por: Muto, Yoshiharu, et al.
Publicado: (2022) -
Cell profiling of mouse acute kidney injury reveals conserved cellular responses to injury
por: Kirita, Yuhei, et al.
Publicado: (2020)