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Structure of the metazoan Rab7 GEF complex Mon1–Ccz1–Bulli

The endosomal system of eukaryotic cells represents a central sorting and recycling compartment linked to metabolic signaling and the regulation of cell growth. Tightly controlled activation of Rab GTPases is required to establish the different domains of endosomes and lysosomes. In metazoans, Rab7...

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Detalles Bibliográficos
Autores principales: Herrmann, Eric, Schäfer, Jan-Hannes, Wilmes, Stephan, Ungermann, Christian, Moeller, Arne, Kümmel, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193976/
https://www.ncbi.nlm.nih.gov/pubmed/37155863
http://dx.doi.org/10.1073/pnas.2301908120