Hematopoietic Jagged1 is a fetal liver niche factor required for functional maturation and engraftment of fetal hematopoietic stem cells

Notch signaling is essential for the emergence of definitive hematopoietic stem cells (HSCs) in the embryo and their development in the fetal liver niche. However, how Notch signaling is activated and which fetal liver cell type provides the ligand for receptor activation in HSCs is unknown. Here we...

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Detalles Bibliográficos
Autores principales: Shao, Lijian, Paik, Na Yoon, Sanborn, Mark A., Bandara, Thilinie, Vijaykumar, Anjali, Sottoriva, Kilian, Rehman, Jalees, Nombela-Arrieta, Cesar, Pajcini, Kostandin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193977/
https://www.ncbi.nlm.nih.gov/pubmed/37155858
http://dx.doi.org/10.1073/pnas.2210058120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193977/
https://www.ncbi.nlm.nih.gov/pubmed/37155858
http://dx.doi.org/10.1073/pnas.2210058120

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