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Zinc treatment reverses and anti-Zn-regulated miRs suppress esophageal carcinomas in vivo

Esophageal squamous cell carcinoma (ESCC) is a deadly disease with few prevention or treatment options. ESCC development in humans and rodents is associated with Zn deficiency (ZD), inflammation, and overexpression of oncogenic microRNAs: miR-31 and miR-21. In a ZD-promoted ESCC rat model with upreg...

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Detalles Bibliográficos
Autores principales: Fong, Louise Y., Huebner, Kay, Jing, Ruiyan, Smalley, Karl J., Brydges, Christopher R., Fiehn, Oliver, Farber, John L., Croce, Carlo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193985/
https://www.ncbi.nlm.nih.gov/pubmed/37155893
http://dx.doi.org/10.1073/pnas.2220334120