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Zinc treatment reverses and anti-Zn-regulated miRs suppress esophageal carcinomas in vivo
Esophageal squamous cell carcinoma (ESCC) is a deadly disease with few prevention or treatment options. ESCC development in humans and rodents is associated with Zn deficiency (ZD), inflammation, and overexpression of oncogenic microRNAs: miR-31 and miR-21. In a ZD-promoted ESCC rat model with upreg...
Autores principales: | Fong, Louise Y., Huebner, Kay, Jing, Ruiyan, Smalley, Karl J., Brydges, Christopher R., Fiehn, Oliver, Farber, John L., Croce, Carlo M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193985/ https://www.ncbi.nlm.nih.gov/pubmed/37155893 http://dx.doi.org/10.1073/pnas.2220334120 |
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