Cargando…
Phosphorylation sites are evolutionary checkpoints against liquid–solid transition in protein condensates
Assemblies of multivalent RNA-binding protein fused in sarcoma (FUS) can exist in the functional liquid-like state as well as less dynamic and potentially toxic amyloid- and hydrogel-like states. How could then cells form liquid-like condensates while avoiding their transformation to amyloids? Here,...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193986/ https://www.ncbi.nlm.nih.gov/pubmed/37155880 http://dx.doi.org/10.1073/pnas.2215828120 |