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Gβγ activates PIP2 hydrolysis by recruiting and orienting PLCβ on the membrane surface
Phospholipase C-βs (PLCβs) catalyze the hydrolysis of phosphatidylinositol 4, 5–bisphosphate [Formula: see text] into [Formula: see text] [Formula: see text] and [Formula: see text] [Formula: see text]. [Formula: see text] regulates the activity of many membrane proteins, while IP3 and DAG lead to...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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National Academy of Sciences
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194004/ https://www.ncbi.nlm.nih.gov/pubmed/37172014 http://dx.doi.org/10.1073/pnas.2301121120 |