Chemiexcitation and melanin in photoreceptor disc turnover and prevention of macular degeneration

Age-related macular degeneration, Stargardt disease, and their Abca4(-/-) mouse model are characterized by accelerated accumulation of the pigment lipofuscin, derived from photoreceptor disc turnover in the retinal pigment epithelium (RPE); lipofuscin accumulation and retinal degeneration both occur...

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Detalles Bibliográficos
Autores principales: Lyu, Yanan, Tschulakow, Alexander V., Wang, Kun, Brash, Douglas E., Schraermeyer, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194005/
https://www.ncbi.nlm.nih.gov/pubmed/37155898
http://dx.doi.org/10.1073/pnas.2216935120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194005/
https://www.ncbi.nlm.nih.gov/pubmed/37155898
http://dx.doi.org/10.1073/pnas.2216935120

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