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Chemiexcitation and melanin in photoreceptor disc turnover and prevention of macular degeneration

Age-related macular degeneration, Stargardt disease, and their Abca4(-/-) mouse model are characterized by accelerated accumulation of the pigment lipofuscin, derived from photoreceptor disc turnover in the retinal pigment epithelium (RPE); lipofuscin accumulation and retinal degeneration both occur...

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Detalles Bibliográficos
Autores principales:	Lyu, Yanan, Tschulakow, Alexander V., Wang, Kun, Brash, Douglas E., Schraermeyer, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194005/ https://www.ncbi.nlm.nih.gov/pubmed/37155898 http://dx.doi.org/10.1073/pnas.2216935120

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